TRARG1 Gene Summary [Human]
Predicted to be involved in endosome to plasma membrane protein transport and glucose import in response to insulin stimulus. Predicted to act upstream of or within vesicle fusion to plasma membrane. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TRARG1 |
| Official Name | trafficking regulator of GLUT4 (SLC2A4) 1 [Source:HGNC Symbol;Acc:HGNC:29592] |
| Ensembl ID | ENSG00000184811 |
| Bio databases IDs | |
| Aliases | trafficking regulator of GLUT4 (SLC2A4) 1, located at seventeen p thirteen point three 1, interferon induced transmembrane protein domain containing 3, dispanin subfamily B member 1, brain endothelial cell derived gene-1 |
| Synonyms | BEC-1, C130069F04Rik, DSPB1, IFITMD3, LOST1, trafficking regulator of GLUT4 (SLC2A4) 1, trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene), TUSC5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TRARG1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytoplasmic vesicle membrane
- perinuclear region
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TRARG1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to insulin stimulus
- glucose import in response to insulin stimulus
- protein localization in plasma membrane
Cellular Component
Where in the cell the gene product is active
- cytoplasmic vesicle membrane
- perinuclear region of cytoplasm
- membrane
- endomembrane system
- plasma membrane