Trarg1 Gene Summary [Mouse]

Involved in endosome to plasma membrane protein transport and glucose import in response to insulin stimulus. Acts upstream of or within establishment of localization in cell and vesicle fusion to plasma membrane. Located in cytoplasmic vesicle membrane; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; nervous system; sensory organ; and white fat. Orthologous to human TRARG1 (trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene)). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Trarg1
Official Name
trafficking regulator of GLUT4 (SLC2A4) 1 [Source:MGI Symbol;Acc:MGI:3029307]
Ensembl ID
ENSMUSG00000046275
Bio databases IDs NCBI: 237858 Ensembl: ENSMUSG00000046275
Aliases trafficking regulator of GLUT4 (SLC2A4) 1
Synonyms BEC-1, C130069F04Rik, DSPB1, IFITMD3, LOST1, trafficking regulator of GLUT4 (SLC2A4) 1, trafficking regulator of GLUT4 (SLC2A4) 1 (gene/pseudogene), TUSC5
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trarg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • osteoarthritis
  • insulin resistance
regulated by
  • TNF
  • 4,5,6,7-tetrabromo-2-azabenzamidazole
  • insulin
regulates
  • 2-deoxyglucose

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cytoplasmic vesicle membrane
  • perinuclear region

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Trarg1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cellular response to insulin stimulus
  • glucose import in response to insulin stimulus
  • protein localization in plasma membrane

Cellular Component

Where in the cell the gene product is active
  • cytoplasmic vesicle membrane
  • perinuclear region of cytoplasm
  • membrane
  • endomembrane system
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.