GALNT17 Gene Summary [Human]
This gene encodes an N-acetylgalactosaminyltransferase. This gene is located centromeric to the common deleted region in Williams-Beuren syndrome (WBS), a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. This protein may play a role in membrane trafficking. [provided by RefSeq, Jan 2013]
Details
| Type | Protein Coding |
| Official Symbol | GALNT17 |
| Official Name | polypeptide N-acetylgalactosaminyltransferase 17 [Source:HGNC Symbol;Acc:HGNC:16347] |
| Ensembl ID | ENSG00000185274 |
| Bio databases IDs | |
| Aliases | polypeptide N-acetylgalactosaminyltransferase 17, polypeptide N-acetylgalactosaminyltransferase-like 3, polypeptide GalNAc transferase 3 |
| Synonyms | E330012B09Rik, GALNACT17, GalNAc-T19, GalNAc-T5L, GALNT16, Galnt19, GALNT20, GALNTL3, Gcap8, polypeptide N-acetylgalactosaminyltransferase 17, WBSCR17 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GALNT17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ricin-type beta-trefoil lectin domain
- Glycosyl transferase family 2
- Ricin-type beta-trefoil
- polypeptide N-acetylgalactosaminyltransferase
- enzyme
- ricin B-type lectin domain, beta-trefoil fold
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GALNT17 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
Cellular Component
Where in the cell the gene product is active
- Golgi membrane
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- carbohydrate binding
- polypeptide N-acetylgalactosaminyltransferase activity