SPIN2B Gene Summary [Human]
Enables methylated histone binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SPIN2B |
| Official Name | spindlin family member 2B [Source:HGNC Symbol;Acc:HGNC:33147] |
| Ensembl ID | ENSG00000186787 |
| Bio databases IDs | |
| Aliases | spindlin family member 2B |
| Synonyms | dJ323P24.2, SPIN-2, SPIN2 duplicate, Spindlin family member 2B, TDRD26 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SPIN2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Spin/Ssty Family
- protein binding activity, bridging
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SPIN2B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
- regulation of transcription, DNA-dependent
- gamete generation
Cellular Component
Where in the cell the gene product is active
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- methylated histone residue binding