LCE1A Gene Summary [Human]
LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 [PubMed 15854049]). For further information on the LCE gene cluster, see GENE FAMILY below.[supplied by OMIM, Feb 2009]
Details
| Type | Protein Coding |
| Official Symbol | LCE1A |
| Official Name | late cornified envelope 1A [Source:HGNC Symbol;Acc:HGNC:29459] |
| Ensembl ID | ENSG00000186844 |
| Bio databases IDs | |
| Aliases | late cornified envelope 1A |
| Synonyms | late cornified envelope 1A, LEP1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LCE1A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LCE1A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- keratinization
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding