CHIC2 Gene Summary [Human]
This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | CHIC2 |
| Official Name | cysteine rich hydrophobic domain 2 [Source:HGNC Symbol;Acc:HGNC:1935] |
| Ensembl ID | ENSG00000109220 |
| Bio databases IDs | |
| Aliases | cysteine rich hydrophobic domain 2 |
| Synonyms | 1700081B18Rik, 4930502K01Rik, BTL, cysteine-rich hydrophobic domain 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CHIC2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Golgin subfamily A member 7/ERF4 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- intracellular membrane-bounded organelle
- cellular membrane
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CHIC2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- Golgi apparatus
- Golgi-associated vesicle
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding