TMPRSS11A Gene Summary [Human]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TMPRSS11A
Official Name
transmembrane serine protease 11A [Source:HGNC Symbol;Acc:HGNC:27954]
Ensembl ID
ENSG00000187054
Bio databases IDs NCBI: 339967 Ensembl: ENSG00000187054
Aliases transmembrane serine protease 11A, airway trypsin-like protease 1
Synonyms ECRG1, HATL1, HESP, transmembrane serine protease 11A
Species
Human, Homo sapiens
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMPRSS11A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • peptidase
  • SEA domain
  • Trypsin-like peptidase domain

Pathways

Biological processes and signaling networks where the TMPRSS11A gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • HA
  • S
role in cell
  • molecular cleavage in
  • spreading in
  • viral entry in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMPRSS11A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • serine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

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