RSPRY1 Gene Summary [Human]

This gene encodes a glycoprotein that contains a RING-type zinc finger domain and an SPRY domain of unknown function. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Details

Type
Protein Coding
Official Symbol
RSPRY1
Official Name
ring finger and SPRY domain containing 1 [Source:HGNC Symbol;Acc:HGNC:29420]
Ensembl ID
ENSG00000159579
Bio databases IDs NCBI: 89970 Ensembl: ENSG00000159579
Aliases ring finger and SPRY domain containing 1
Synonyms 4930470D19Rik, RGD1308847, ring finger and SPRY domain containing 1, SEMDFA
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RSPRY1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SPRY domain
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger domain
  • Zinc finger, C3HC4 type (RING finger)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Faden-Alkuraya type spondyloepimetaphyseal dysplasia

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RSPRY1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis involved in cellular protein catabolic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • ubiquitin-protein ligase activity
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

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