ZSCAN23 Gene Summary [Human]

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
ZSCAN23
Official Name
zinc finger and SCAN domain containing 23 [Source:HGNC Symbol;Acc:HGNC:21193]
Ensembl ID
ENSG00000187987
Bio databases IDs NCBI: 222696 Ensembl: ENSG00000187987
Aliases zinc finger and SCAN domain containing 23
Synonyms dJ29K1.3, dJ29K1.3.1, LOC105374997, zinc finger and SCAN domain containing 23, ZNF390, ZNF453
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZSCAN23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc finger, C2H2 type
  • leucine rich region
  • transcription regulator
  • double-stranded DNA binding
  • Zinc-finger double domain
  • SCAN domain
  • protein binding
  • sequence-specific DNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • inflammatory bowel disease
  • schizophrenia
  • systemic lupus erythematosus
  • multiple sclerosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZSCAN23 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.