GAGE2A Gene Summary [Human]
This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | GAGE2A |
| Official Name | G antigen 2A [Source:HGNC Symbol;Acc:HGNC:4099] |
| Ensembl ID | ENSG00000189064 |
| Bio databases IDs | |
| Aliases | G antigen 2A, cancer/testis antigen family 4, member 2 |
| Synonyms | CT4.8, G antigen 8 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GAGE2A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GAGE protein
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GAGE2A gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- protein binding