KCTD6 Gene Summary [Human]
Enables ankyrin binding activity; cullin family protein binding activity; and identical protein binding activity. Involved in negative regulation of smoothened signaling pathway and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | KCTD6 |
| Official Name | potassium channel tetramerization domain containing 6 [Source:HGNC Symbol;Acc:HGNC:22235] |
| Ensembl ID | ENSG00000168301 |
| Bio databases IDs | |
| Aliases | potassium channel tetramerization domain containing 6 |
| Synonyms | 5430433B02RIK, CTB57, KCASH3, Kctd6 predicted, potassium channel tetramerisation domain containing 6, potassium channel tetramerization domain containing 6 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KCTD6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ankyrin binding
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
- identical protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KCTD6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein homooligomerization
- negative regulation of smoothened signaling pathway
- ubiquitin-dependent protein catabolic process
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- cytosol
- M band
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- ankyrin binding