IPP Gene Summary [Human]
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 50 amino acid repeat which interacts with actin. Transcript variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | IPP |
| Official Name | intracisternal A particle-promoted polypeptide [Source:HGNC Symbol;Acc:HGNC:6108] |
| Ensembl ID | ENSG00000197429 |
| Bio databases IDs | |
| Aliases | intracisternal A particle-promoted polypeptide, kelch-like family member 27 |
| Synonyms | D4Jhu8, IAP promoted placental gene, intracisternal A particle-promoted polypeptide, KLHL27, Mipp |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IPP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Galactose oxidase, central domain
- Kelch motif
- BTB And C-terminal Kelch
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- actin binding
- BTB/POZ domain
- protein binding
- BACK (BTB and C-terminal Kelch) domain
- Kelch domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- actin cytoskeleton
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IPP gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- actin cytoskeleton
Molecular Function
What the gene product does at the molecular level
- actin binding