MEIG1 Gene Summary [Human]

Predicted to act upstream of or within cellular protein localization; manchette assembly; and sperm axoneme assembly. Predicted to be located in cytosol and manchette. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
MEIG1
Official Name
meiosis/spermiogenesis associated 1 [Source:HGNC Symbol;Acc:HGNC:23429]
Ensembl ID
ENSG00000197889
Bio databases IDs NCBI: 644890 Ensembl: ENSG00000197889
Aliases meiosis/spermiogenesis associated 1, spermatogenesis associated 39
Synonyms bA2K17.3, LOC105376430, LOC683735, Meg1, meiosis expressed gene 1, meiosis/spermiogenesis associated 1, MLZ-278, SPATA39
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MEIG1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Meiosis-expressed
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • asthenozoospermia
  • oligozoospermia
  • azoospermia
  • teratozoospermia
regulated by
role in cell
  • apoptosis
  • abnormal morphology
  • lack
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • manchette
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MEIG1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein localization
  • sperm axoneme assembly

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol
  • manchette

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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