Meig1 Gene Summary [Mouse]
Acts upstream of or within manchette assembly; protein localization; and sperm axoneme assembly. Located in cytosol; manchette; and nucleus. Is expressed in ovary; retina; and testis. Orthologous to human MEIG1 (meiosis/spermiogenesis associated 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Meig1 |
| Official Name | meiosis expressed gene 1 [Source:MGI Symbol;Acc:MGI:1202878] |
| Ensembl ID | ENSMUSG00000026650 |
| Bio databases IDs | |
| Aliases | meiosis expressed gene 1 |
| Synonyms | bA2K17.3, LOC105376430, LOC683735, Meg1, meiosis expressed gene 1, meiosis/spermiogenesis associated 1, MLZ-278, SPATA39 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Meig1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Meiosis-expressed
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- manchette
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Meig1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein localization
- sperm axoneme assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- manchette
Molecular Function
What the gene product does at the molecular level
- protein binding