KRTAP4-1 Gene Summary [Human]
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | KRTAP4-1 |
| Official Name | keratin associated protein 4-1 [Source:HGNC Symbol;Acc:HGNC:18907] |
| Ensembl ID | ENSG00000198443 |
| Bio databases IDs | |
| Aliases | keratin associated protein 4-1 |
| Synonyms | KAP4.1, KAP4.10, keratin associated protein 4-1, KRTAP4-10, KRTAP4.10 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KRTAP4-1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Keratin, high sulfur B2 protein
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KRTAP4-1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- keratin filament
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding