OXCT2 Gene Summary [Human]
The protein encoded by this gene catalyzes the transfer of a CoA group from succinate to acetoacetate and is an important enzyme in ketone body catabolism. The encoded protein localizes to the mitochondrion. This gene is intronless, and a pseudogene of this gene is located elsewhere on chromosome 1. [provided by RefSeq, Aug 2016]
Details
| Type | Protein Coding |
| Official Symbol | OXCT2 |
| Official Name | 3-oxoacid CoA-transferase 2 [Source:HGNC Symbol;Acc:HGNC:18606] |
| Ensembl ID | ENSG00000198754 |
| Bio databases IDs | |
| Aliases | 3-oxoacid CoA-transferase 2 |
| Synonyms | 3-oxoacid CoA-transferase 2, 3-oxoacid CoA transferase 2B, FKSG25, LOC100365119, Oxct2a, Oxct2b, SCOTT, SCOT-t1, Scot-t2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OXCT2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SugarP_isomerase
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OXCT2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ketone body catabolic process
- cellular ketone body metabolic process
Cellular Component
Where in the cell the gene product is active
- motile cilium
- mitochondrial matrix
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- 3-oxoacid CoA-transferase activity