OOEP Gene Summary [Human]
Predicted to enable RNA binding activity. Predicted to be involved in several processes, including cytoskeleton organization; positive regulation of double-strand break repair via homologous recombination; and positive regulation of meiotic nuclear division. Predicted to act upstream of or within several processes, including embryo implantation; in utero embryonic development; and protein phosphorylation. Located in cytoplasm and nucleus. Part of subcortical maternal complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | OOEP |
| Official Name | oocyte expressed protein [Source:HGNC Symbol;Acc:HGNC:21382] |
| Ensembl ID | ENSG00000203907 |
| Bio databases IDs | |
| Aliases | oocyte expressed protein, KH homology domain containing 2 |
| Synonyms | 2410146L05Rik, C6orf156, FLOPED, HOEP19, KHDC2, LOC124901341, Moep19, oocyte expressed protein, RGD1311103, Sddr |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human OOEP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- K homology (KH) RNA-binding domain, type I
- KH-like RNA-binding domain
- protein binding
- structural molecule
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- organelle
- apical compartment
- cell cortex
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human OOEP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- establishment or maintenance of apical/basal cell polarity
- regulation of cell division
- positive regulation of meiosis
- regulation of protein localization
- embryonic pattern specification
- establishment of spindle localization
- actin filament organization
- replication fork processing
- regulation of establishment of protein localization
- positive regulation of double-strand break repair
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cell cortex
- macromolecular complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding