IGFL2 Gene Summary [Human]

IGFL2 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).[supplied by OMIM, Mar 2008]

Details

Type
Processed Transcript
Official Symbol
IGFL2
Official Name
IGF like family member 2 [Source:HGNC Symbol;Acc:HGNC:32929]
Ensembl ID
ENSG00000204866
Bio databases IDs NCBI: 147920 Ensembl: ENSG00000204866
Aliases IGF like family member 2
Synonyms IGF like family member 2, LOC124908086, UNQ645, VPRI645
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IGFL2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Insulin growth factor-like family
  • protein binding
  • receptor binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Sézary syndrome
  • liver cancer
  • epithelial neoplasia
  • epithelial cancer
  • cervical cancer
  • breast carcinoma
  • urothelial bladder carcinoma
  • transitional cell bladder cancer
  • acute myeloid leukemia
  • organismal death
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human IGFL2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular space

Molecular Function

What the gene product does at the molecular level
  • receptor binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.