MTCP1 Gene Summary [Human]
This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets of 3' exons that encode two different proteins. This gene represents the upstream 13 kDa protein that is a member of the TCL1 family. This protein may be involved in leukemogenesis. [provided by RefSeq, Mar 2009]
Details
| Type | Protein Coding |
| Official Symbol | MTCP1 |
| Official Name | mature T cell proliferation 1 [Source:HGNC Symbol;Acc:HGNC:7423] |
| Ensembl ID | ENSG00000214827 |
| Bio databases IDs | |
| Aliases | mature T cell proliferation 1, TCL1 family AKT coactivator C |
| Synonyms | mature T-cell proliferation 1, P13MTCP1, p8MTCP1, RGD1561352, TCL1C |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MTCP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase activator
- protein kinase binding
- TCL1/MTCP1 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- severe hemophilia A and moyamoya syndrome
- X-linked Moyamoya disease
- T-cell prolymphocytic leukemia
regulates
role in cell
- proliferation
- quantity
- development
- morphology
- condensation
- signal transduction in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MTCP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- intracellular signal transduction
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- protein serine/threonine kinase activator activity