STPG4 Gene Summary [Human]
Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in DNA demethylation of male pronucleus and positive regulation of DNA demethylation. Predicted to act upstream of or within C-5 methylation of cytosine. Predicted to be located in cytoplasm and nucleus. Predicted to be active in female pronucleus; germinal vesicle; and male pronucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | STPG4 |
| Official Name | sperm-tail PG-rich repeat containing 4 [Source:HGNC Symbol;Acc:HGNC:26850] |
| Ensembl ID | ENSG00000239605 |
| Bio databases IDs | |
| Aliases | sperm-tail PG-rich repeat containing 4 |
| Synonyms | 1700011E24Rik, C2orf61, GSE, RP11 761B31, sperm-tail PG-rich repeat containing 4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STPG4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone binding
- chromatin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nucleoplasm
- pronucleus
- germinal vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STPG4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- 5-methylcytosine catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- male pronucleus
- cytoplasm
- germinal vesicle
- female pronucleus
- male germ cell nucleus
Molecular Function
What the gene product does at the molecular level
- histone binding
- chromatin binding