KRTAP4-7 Gene Summary [Human]
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Mar 2009]
Details
| Type | Protein Coding |
| Official Symbol | KRTAP4-7 |
| Official Name | keratin associated protein 4-7 [Source:HGNC Symbol;Acc:HGNC:18898] |
| Ensembl ID | ENSG00000240871 |
| Bio databases IDs | |
| Aliases | keratin associated protein 4-7 |
| Synonyms | KAP4.7, keratin associated protein 4-7, KRTAP4.7 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KRTAP4-7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Keratin, high sulfur B2 protein
- PMG protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown