PNLIPRP2 Gene Summary [Human]
This gene encodes a lipase that hydrolyzes galactolipids, the main components of plant membrane lipids. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the non-coding allele. [provided by RefSeq, Aug 2015]
Details
| Type | Polymorphic Pseudogene |
| Official Symbol | PNLIPRP2 |
| Official Name | pancreatic lipase related protein 2 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:9157] |
| Ensembl ID | ENSG00000266200 |
| Bio databases IDs | |
| Aliases | pancreatic lipase related protein 2 (gene/pseudogene) |
| Synonyms | pancreatic lipase related protein 2, pancreatic lipase related protein 2 (gene/pseudogene), PLRP2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PNLIPRP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolases
- acylglycerol lipase
- PLAT
- lipase
- calcium ion binding
- galactolipase
- enzyme
- protein binding
- lipoprotein lipase
- Lipoxygenase homology 2 (beta barrel) domain
- phospholipase
- triacylglycerol lipase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- zymogen granules
- neurites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PNLIPRP2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylcholine catabolic process
- lipid digestion
- phospholipid catabolic process
- galactolipid catabolic process
- triglyceride metabolic process
- triglyceride catabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular region
- neuron projection
- zymogen granule membrane
Molecular Function
What the gene product does at the molecular level
- acylglycerol lipase activity
- calcium ion binding
- triglyceride lipase activity
- galactolipase activity
- phospholipase activity