Pnliprp2 Gene Summary [Rat]

Enables galactolipase activity; phospholipase activity; and triacylglycerol lipase activity. Involved in several processes, including galactolipid catabolic process; response to food; and response to glucocorticoid. Located in extracellular space; neuron projection; and zymogen granule membrane. Orthologous to human PNLIPRP2 (pancreatic lipase related protein 2 (gene/pseudogene)). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pnliprp2
Official Name
pancreatic lipase related protein 2 [Source:RGD Symbol;Acc:620793]
Ensembl ID
ENSRNOG00000017982
Bio databases IDs NCBI: 117554 Ensembl: ENSRNOG00000017982
Aliases pancreatic lipase related protein 2
Synonyms pancreatic lipase related protein 2, pancreatic lipase related protein 2 (gene/pseudogene), PLRP2
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pnliprp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha/beta hydrolases
  • acylglycerol lipase
  • PLAT
  • lipase
  • calcium ion binding
  • galactolipase
  • enzyme
  • protein binding
  • lipoprotein lipase
  • Lipoxygenase homology 2 (beta barrel) domain
  • phospholipase
  • triacylglycerol lipase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • dexamethasone
  • elaidic acid
regulates
  • fatty acid
  • lipid
  • phosphatidylcholine
  • glycerol
  • phospholipid
  • triacylglycerol
  • retinyl ester
role in cell
  • endoplasmic reticulum stress response in
  • re-esterification in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • cellular membrane
  • zymogen granules
  • neurites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pnliprp2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phosphatidylcholine catabolic process
  • lipid digestion
  • phospholipid catabolic process
  • galactolipid catabolic process
  • triglyceride metabolic process
  • triglyceride catabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular region
  • neuron projection
  • zymogen granule membrane

Molecular Function

What the gene product does at the molecular level
  • acylglycerol lipase activity
  • calcium ion binding
  • triglyceride lipase activity
  • galactolipase activity
  • phospholipase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.