Narf Gene Summary [Mouse]
Predicted to enable lamin binding activity. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in lamin filament. Is expressed in liver lobe; nervous system; and neural retina. Orthologous to human NARF (nuclear prelamin A recognition factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Narf |
| Official Name | nuclear prelamin A recognition factor [Source:MGI Symbol;Acc:MGI:1914858] |
| Ensembl ID | ENSMUSG00000000056 |
| Bio databases IDs | |
| Aliases | nuclear prelamin A recognition factor |
| Synonyms | 4430402O11Rik, IOP2, LOC102550455, nuclear prelamin A recognition factor, RGD1310894 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Narf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Iron hydrogenase small subunit
- [FeFe] hydrogenase, group A
- lamin binding
- enzyme
- Iron only hydrogenase large subunit, C-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
- nuclear envelope
- nuclear lamina
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Narf gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- lamin filament
- nuclear lumen
- nucleolus
- nuclear lamina
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- lamin binding