Usp32 Gene Summary [Mouse]

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in positive regulation of TORC1 signaling. Predicted to be located in cytosol. Predicted to be active in Golgi apparatus. Is expressed in choroid plexus; cranial ganglion; and dorsal root ganglion. Orthologous to several human genes including USP32 (ubiquitin specific peptidase 32). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Usp32
Official Name
ubiquitin specific peptidase 32 [Source:MGI Symbol;Acc:MGI:2144475]
Ensembl ID
ENSMUSG00000000804
Bio databases IDs NCBI: 237898 Ensembl: ENSMUSG00000000804
Aliases ubiquitin specific peptidase 32
Synonyms 2900074J03Rik, 6430526O11Rik, NY-REN-60, ubiquitin specific peptidase 32, USP10
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Usp32 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EF-hand domain pair
  • peptidase
  • ubiquitin-specific protease
  • EFh
  • protein binding
  • ubiquitin-like domain

Pathways

Biological processes and signaling networks where the Usp32 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
regulated by
regulates
role in cell
  • growth
  • dipeptide repeat protein sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Usp32 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein deubiquitination
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • Golgi apparatus
  • Golgi membrane

Molecular Function

What the gene product does at the molecular level
  • ubiquitin-specific protease activity
  • protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.