Wfdc18 Gene Summary [Mouse]

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in mammary gland. [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Wfdc18
Official Name
WAP four-disulfide core domain 18 [Source:MGI Symbol;Acc:MGI:107506]
Ensembl ID
ENSMUSG00000000983
Bio databases IDs NCBI: 14038 Ensembl: ENSMUSG00000000983
Aliases WAP four-disulfide core domain 18
Synonyms Expi, Extracellular protease inhibitor, Kal1, WAP four-disulfide core domain 18, WDNM1
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wfdc18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WAP
  • WAP-type (Whey Acidic Protein) 'four-disulfide core'

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dextran sodium sulfate-induced colitis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.