Rundc3a Gene Summary [Mouse]
Predicted to be involved in positive regulation of cGMP-mediated signaling. Predicted to be located in intracellular membrane-bounded organelle. Is expressed in several structures, including adrenal gland; gut; nervous system; nose; and retina. Orthologous to human RUNDC3A (RUN domain containing 3A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rundc3a |
| Official Name | RUN domain containing 3A [Source:MGI Symbol;Acc:MGI:1858752] |
| Ensembl ID | ENSMUSG00000006575 |
| Bio databases IDs | |
| Aliases | RUN domain containing 3A |
| Synonyms | GCRP, RAP2IP, RPIP-8, RUN domain containing 3A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rundc3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTPase regulator
- domain involved in Ras-like GTPase signaling
- protein binding
- RUN domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rundc3a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- small GTPase mediated signal transduction
- positive regulation of cGMP-mediated signaling
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
Molecular Function
What the gene product does at the molecular level
- protein binding
- GTPase regulator activity