Phax Gene Summary [Mouse]

Predicted to enable mRNA cap binding complex binding activity and toxic substance binding activity. Acts upstream of or within snRNA export from nucleus. Located in cytoplasm and nucleus. Orthologous to human PHAX (phosphorylated adaptor for RNA export). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Phax
Official Name
phosphorylated adaptor for RNA export [Source:MGI Symbol;Acc:MGI:1891839]
Ensembl ID
ENSMUSG00000008301
Bio databases IDs NCBI: 56698 Ensembl: ENSMUSG00000008301
Aliases phosphorylated adaptor for RNA export
Synonyms 2810055C14Rik, 4933427L19Rik, D18Ertd65e, p55, phosphorylated adaptor for RNA export, RNUXA
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Phax often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • Phosphorylated adapter RNA export protein, RNA-binding domain
  • protein binding
  • toxin binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
  • acute myeloid leukemia
  • estrogen receptor-negative breast cancer
  • bipolar disorder
regulated by
  • gentamicin
regulates
  • snRNP
  • CBC
role in cell
  • replication in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol
  • nucleoplasm
  • perikaryon

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Phax gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • snRNA export from nucleus
  • protein transport
  • RNA stabilization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • Cajal body
  • cytosol
  • neuronal cell body
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • toxin binding
  • RNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

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