Dhdh Gene Summary [Mouse]
Enables D-xylose 1-dehydrogenase (NADP+) activity. Acts upstream of or within D-xylose catabolic process. Is expressed in nervous system and respiratory system. Orthologous to human DHDH (dihydrodiol dehydrogenase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dhdh |
| Official Name | dihydrodiol dehydrogenase (dimeric) [Source:MGI Symbol;Acc:MGI:1919005] |
| Ensembl ID | ENSMUSG00000011382 |
| Bio databases IDs | |
| Aliases | dihydrodiol dehydrogenase (dimeric) |
| Synonyms | 1300018L09RIK, 2DD, B830008H07Rik, dihydrodiol dehydrogenase, HUM2DD, Xld1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dhdh often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rossmann-fold NAD(P)(+)-binding proteins
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
- Oxidoreductase family, C-terminal alpha/beta domain
- D-xylose 1-dehydrogenase (NADP)
- Oxidoreductase family, NAD-binding Rossmann fold
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dhdh gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- D-xylose catabolic process
Molecular Function
What the gene product does at the molecular level
- nucleotide binding
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
- D-xylose 1-dehydrogenase (NADP+) activity