Kctd5 Gene Summary [Mouse]
Predicted to enable cullin family protein binding activity and identical protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in central nervous system and genitourinary system. Orthologous to human KCTD5 (potassium channel tetramerization domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kctd5 |
| Official Name | potassium channel tetramerisation domain containing 5 [Source:MGI Symbol;Acc:MGI:1916509] |
| Ensembl ID | ENSMUSG00000016946 |
| Bio databases IDs | |
| Aliases | potassium channel tetramerisation domain containing 5 |
| Synonyms | 2610030N08RIK, FLJ20040, Kctd5 predicted, mKIAA0176, potassium channel tetramerisation domain containing 5, potassium channel tetramerization domain containing 5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kctd5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- prostatic adenocarcinoma
- prostate cancer
- cancer
- epithelial thyroid cancer
- epithelial cancer
- epithelial neoplasia
- ovarian serous cystadenocarcinoma
- serous ovarian cancer
- lung adenocarcinoma formation
- diffuse large B-cell lymphoma
regulated by
- myoblasts
- hepatitis B virus
regulates
- zymosan
- Myelin
role in cell
- proliferation
- apoptosis
- migration
- phagocytosis
- phagocytosis by
- contractility
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kctd5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteasomal ubiquitin-dependent protein catabolic process
- protein homooligomerization
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- Cul3-RING ubiquitin ligase complex
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding