Gsdma Gene Summary [Mouse]
Predicted to enable phospholipid binding activity and wide pore channel activity. Predicted to be involved in defense response to bacterium and pyroptotic inflammatory response. Located in cytoplasm. Is expressed in foregut and skin. Orthologous to human GSDMA (gasdermin A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gsdma |
| Official Name | gasdermin A [Source:MGI Symbol;Acc:MGI:1889509] |
| Ensembl ID | ENSMUSG00000017204 |
| Bio databases IDs | |
| Aliases | gasdermin A |
| Synonyms | gasdermin A, Gsdm, Gsdm1, Gsdma1, H312E |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gsdma often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- channel/pore class transporter
- Gasdermin PUB domain
- Gasdermin pore forming domain
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- cellular membrane