Ppp2r3c Gene Summary [Mouse]
Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including lymphocyte homeostasis; positive regulation of B cell differentiation; and spleen development. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be active in centrosome. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and embryo. Human ortholog(s) of this gene implicated in spermatogenic failure 36. Orthologous to human PPP2R3C (protein phosphatase 2 regulatory subunit B''gamma). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppp2r3c |
| Official Name | protein phosphatase 2, regulatory subunit B'', gamma [Source:MGI Symbol;Acc:MGI:1930009] |
| Ensembl ID | ENSMUSG00000021022 |
| Bio databases IDs | |
| Aliases | protein phosphatase 2, regulatory subunit B'', gamma |
| Synonyms | 4930511A21Rik, 5730412A08Rik, G4-1, G5pr, protein phosphatase 2, regulatory subunit B'', gamma, protein phosphatase 2, regulatory subunit B'', γ |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp2r3c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- serine/threonine protein phosphatase 2A regulatory subunit B''
- EF-hand domain
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- Golgi Apparatus
- cytosol
- nucleoplasm