Tecpr2 Gene Summary [Mouse]
Predicted to be involved in protein exit from endoplasmic reticulum. Is expressed in olfactory epithelium. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 49. Orthologous to human TECPR2 (tectonin beta-propeller repeat containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tecpr2 |
| Official Name | tectonin beta-propeller repeat containing 2 [Source:MGI Symbol;Acc:MGI:2144865] |
| Ensembl ID | ENSMUSG00000021275 |
| Bio databases IDs | |
| Aliases | tectonin beta-propeller repeat containing 2 |
| Synonyms | 4930573I19Rik, HSAN9, KIAA0329, mKIAA0297, RGD1307503, SPG49, tectonin beta-propeller repeat containing 2, tectonin β-propeller repeat containing 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tecpr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TECPR
- Tectonin domain
- protein binding
- Propeller
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- autosomal recessive spastic paraplegia type 49
- hereditary spastic paraplegia
- autism
- myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis
- sporadic parathyroid adenoma
- parathyroid adenoma
- birdshot chorioretinopathy
- global developmental delay with intellectual disability
- hereditary disorder
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tecpr2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein exit from endoplasmic reticulum
- autophagy
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding