Gtpbp8 Gene Summary [Mouse]

Predicted to enable GTP binding activity and metal ion binding activity. Located in mitochondrion. Orthologous to human GTPBP8 (GTP binding protein 8). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Gtpbp8
Official Name
GTP-binding protein 8 (putative) [Source:MGI Symbol;Acc:MGI:1913317]
Ensembl ID
ENSMUSG00000022668
Bio databases IDs NCBI: 66067 Ensembl: ENSMUSG00000022668
Aliases GTP-binding protein 8 (putative)
Synonyms 0610037H22Rik, GTP binding protein 8, GTP-binding protein 8 (putative), HSPC135, RGD1310025
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gtpbp8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • small GTP-binding protein domain
  • ribosome biogenesis GTP-binding protein YsxC/EngB
  • 50S ribosome-binding GTPase
  • protein binding
  • Elongation factor Tu GTP binding domain
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • non-insulin-dependent diabetes mellitus
  • breast adenocarcinoma
  • major depression
  • cervical cancer
  • Alzheimer disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gtpbp8 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.