Cfap91 Gene Summary [Mouse]
Predicted to be involved in axonemal central apparatus assembly; cilium movement; and spermatogenesis. Predicted to be located in axoneme and motile cilium. Predicted to be part of radial spoke stalk. Is expressed in choroid invagination; diencephalon roof plate; lung; and metencephalon part of 4th ventricle choroid plexus. Human ortholog(s) of this gene implicated in spermatogenic failure 51. Orthologous to human CFAP91 (cilia and flagella associated protein 91). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cfap91 |
| Official Name | cilia and flagella associated protein 91 [Source:MGI Symbol;Acc:MGI:2443598] |
| Ensembl ID | ENSMUSG00000022805 |
| Bio databases IDs | |
| Aliases | cilia and flagella associated protein 91 |
| Synonyms | 4932425I24Rik, AAT1, C3orf15, CaM-IP2, cilia and flagella associated protein 91, MAATS1, RGD1305539, SPATA26, SPGF51 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cfap91 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Cilia- and flagella-associated protein 91
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- Nucleus
- Mitochondria
- axonemes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cfap91 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spermatogenesis
- cell differentiation
- cilium movement
Cellular Component
Where in the cell the gene product is active
- motile cilium
- radial spoke stalk
- mitochondrion
- axoneme
Molecular Function
What the gene product does at the molecular level
- protein binding