Rpp14 Gene Summary [Mouse]
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be part of multimeric ribonuclease P complex. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human RPP14 (ribonuclease P/MRP subunit p14). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpp14 |
| Official Name | ribonuclease P 14 subunit [Source:MGI Symbol;Acc:MGI:1914303] |
| Ensembl ID | ENSMUSG00000023156 |
| Bio databases IDs | |
| Aliases | ribonuclease P 14 subunit |
| Synonyms | hydroxyacyl-thioester dehydratase type 2, RP11-80H18.3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpp14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MaoC like domain
- 3-hydroxyacyl-CoA dehydratase
- hot_dog
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpp14 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty-acyl-CoA biosynthetic process
- fatty acid biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- nucleolus
Molecular Function
What the gene product does at the molecular level
- 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
- 3-hydroxyacyl-CoA dehydratase activity
- 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity