Bysl Gene Summary [Mouse]
Predicted to enable snoRNA binding activity. Acts upstream of or within maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); stem cell proliferation; and trophectodermal cell differentiation. Located in apical part of cell; cytoplasm; and nucleolus. Is expressed in several structures, including bone marrow; early conceptus; intestine; liver; and reproductive system. Orthologous to human BYSL (bystin like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bysl |
| Official Name | bystin-like [Source:MGI Symbol;Acc:MGI:1858419] |
| Ensembl ID | ENSMUSG00000023988 |
| Bio databases IDs | |
| Aliases | bystin-like |
| Synonyms | Bys, BYSTIN, bystin-like, ENP1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bysl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Bystin
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colon cancer
- endometriosis
- colorectal adenoma
- colorectal adenoma formation
regulates
- Ribosomal Subunit 40s
role in cell
- proliferation
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- cytoskeleton
- Cytoplasm
- apical compartment
- perinuclear region
- Plasma Membrane
- cytosol
- chromosome
- nucleoplasm
- nucleoli
- cytoplasmic microtubule
- cellular protrusions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bysl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- stem cell proliferation
- ribosome biogenesis
- rRNA processing
- trophectodermal cell differentiation
Cellular Component
Where in the cell the gene product is active
- apical part of cell
- cytoplasm
- intracellular membrane-bounded organelle
- membrane
- cytosol
- chromosome
- nucleolus
- preribosome, small subunit precursor
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- snoRNA binding
- protein binding
- RNA binding