Slc13a1 Gene Summary [Mouse]
Enables sodium:sulfate symporter activity. Acts upstream of or within sulfate transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; metanephros; musculoskeletal system; and sensory organ. Orthologous to human SLC13A1 (solute carrier family 13 member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc13a1 |
| Official Name | solute carrier family 13 (sodium/sulfate symporters), member 1 [Source:MGI Symbol;Acc:MGI:1859937] |
| Ensembl ID | ENSMUSG00000029700 |
| Bio databases IDs | |
| Aliases | solute carrier family 13 (sodium/sulfate symporters), member 1 |
| Synonyms | NAS1, NaSi-1, solute carrier family 13 member 1, solute carrier family 13 (sodium/sulfate symporters), solute carrier family 13 (sodium/sulfate symporters), member 1, solute carrier family 13 (sodium/sulphate symporters), member 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc13a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- sulfate porter
- sodium:sulfate symporter
- ArsB_NhaD_permease
- monovalent anion:sodium symporter
- transporter
- citrate transporter
- anion transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- Alzheimer disease
- clonic seizure
- backache
- hyposulfatemia
- hypersulfaturia
- growth failure
- spondyloepimetaphyseal dysplasia
- proximal tubular toxicity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- apical membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc13a1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sulfate transport
- sodium ion transport
- transmembrane transport
- sodium ion transmembrane transport
Cellular Component
Where in the cell the gene product is active
- apical plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- monovalent anion:sodium symporter activity
- sodium:sulfate symporter activity