Tpsab1 Gene Summary [Mouse]
Enables peptidase activity. Acts upstream of or within proteolysis. Located in extracellular space and mast cell granule. Is expressed in several structures, including alimentary system; brain; immune system; integumental system; and reproductive system. Orthologous to several human genes including TPSD1 (tryptase delta 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tpsab1 |
| Official Name | tryptase alpha/beta 1 [Source:MGI Symbol;Acc:MGI:96943] |
| Ensembl ID | ENSMUSG00000024173 |
| Bio databases IDs | |
| Aliases | tryptase alpha/beta 1 |
| Synonyms | Mast cell tryptase, Mcp-7, Mcpt7, MMCP-7, tryptase alpha/beta 1, tryptase α/β 1 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tpsab1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- peptidase
- identical protein binding
Pathways
Biological processes and signaling networks where the Tpsab1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Extracellular Space
- lysosome