Cyp4f14 Gene Summary [Mouse]

Predicted to enable arachidonate binding activity; heme binding activity; and monooxygenase activity. Predicted to be involved in leukotriene B4 catabolic process and omega-hydroxylase P450 pathway. Predicted to be located in apical plasma membrane; cytoplasm; and intracellular membrane-bounded organelle. Is expressed in liver; nervous system; and testis. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to several human genes including CYP4F2 (cytochrome P450 family 4 subfamily F member 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cyp4f14
Official Name
cytochrome P450, family 4, subfamily f, polypeptide 14 [Source:MGI Symbol;Acc:MGI:1927669]
Ensembl ID
ENSMUSG00000024292
Bio databases IDs NCBI: 64385 Ensembl: ENSMUSG00000024292
Aliases cytochrome P450, family 4, subfamily f, polypeptide 14
Synonyms 1300014O15Rik, Cyp4f1, Cyp4f2, cytochrome P450, family 4, subfamily f, polypeptide 1, cytochrome P450, family 4, subfamily f, polypeptide 14
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cyp4f14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • cytochrome P450 (CYP) superfamily
  • Cytochrome P450
  • reduced flavin or flavoprotein:oxygen oxidoreductase
  • fatty acid binding
  • leukotriene-B4 20-monooxygenase
  • arachidonic acid binding
  • enzyme
  • heme binding
  • arachidonic acid epoxygenase
  • NADH2 or NADPH2 1 atom incorporation:oxygen oxidoreductase
  • alkane 1-monooxygenase
  • arachidonic acid monooxygenase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • arachidonic acid
  • gamma tocopherol
  • delta-tocopherol
  • 12'-hydroxy-gamma-tocopherol
  • 11'-hydroxy-gamma-tocopherol
  • leukotriene B4
  • alpha-tocopherol
  • eicosanoid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • Endoplasmic Reticulum
  • apical membrane

Gene-Specific Assays for Results You Can Trust

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