Pnliprp2 Gene Summary [Mouse]

Enables triacylglycerol lipase activity. Acts upstream of or within cellular defense response; intestinal lipid catabolic process; and response to bacterium. Predicted to be located in neuron projection and zymogen granule membrane. Predicted to be active in extracellular space. Is expressed in pancreas tip epithelium. Orthologous to human PNLIPRP2 (pancreatic lipase related protein 2 (gene/pseudogene)). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pnliprp2
Official Name
pancreatic lipase-related protein 2 [Source:MGI Symbol;Acc:MGI:1336202]
Ensembl ID
ENSMUSG00000025091
Bio databases IDs NCBI: 18947 Ensembl: ENSMUSG00000025091
Aliases pancreatic lipase-related protein 2
Synonyms pancreatic lipase-related protein 2, PLRP2
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pnliprp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • alpha/beta hydrolases
  • lipase
  • acylglycerol lipase
  • PLAT
  • calcium ion binding
  • galactolipase
  • enzyme
  • lipoprotein lipase
  • Lipoxygenase homology 2 (beta barrel) domain
  • phospholipase
  • triacylglycerol lipase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • histone H3
  • tricaprilin
disease
  • diabetes mellitus
regulated by
regulates
  • triolein
  • tricaprilin
  • phosphatidylcholine
  • digalactosyldiacylglycerol
  • tributyrin
role in cell
  • response

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • zymogen granules
  • neurites

Gene-Specific Assays for Results You Can Trust

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