Slc28a2 Gene Summary [Mouse]

Enables purine nucleoside transmembrane transporter activity. Predicted to be involved in several processes, including nucleoside transport; protein localization to cell surface; and purine nucleobase transmembrane transport. Located in brush border membrane. Is expressed in foregut-midgut junction; midgut; and placenta. Orthologous to human SLC28A2 (solute carrier family 28 member 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Slc28a2
Official Name
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 [Source:MGI Symbol;Acc:MGI:1913105]
Ensembl ID
ENSMUSG00000027219
Bio databases IDs NCBI: 269346 Ensembl: ENSMUSG00000027219
Aliases solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
Synonyms 2010208B10Rik, B430217P18, BB152493, Cnt2, solute carrier family 28 (sodium-coupled nucleoside transporter), member 2, SPNT
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc28a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • uridine transporter
  • purine transporter
  • purine nucleoside transporter
  • nucleoside transporter
  • Nucleoside recognition
  • pyrimidine- and adenine-specific:sodium symporter
  • neurotransmitter transporter
  • Na+ dependent nucleoside transporter C-terminus
  • Na+ dependent nucleoside transporter N-terminus
  • transporter
  • nucleoside:sodium symporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • purine nucleoside
  • inosine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • apicolateral membrane
  • cellular membrane
  • vesicles
  • vesicle membrane
  • brush border

Gene-Specific Assays for Results You Can Trust

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