Fahd2a Gene Summary [Mouse]
Predicted to enable oxaloacetate tautomerase activity. Predicted to be involved in oxaloacetate metabolic process. Located in mitochondrion. Orthologous to several human genes including FAHD2A (fumarylacetoacetate hydrolase domain containing 2A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fahd2a |
| Official Name | fumarylacetoacetate hydrolase domain containing 2A [Source:MGI Symbol;Acc:MGI:1915376] |
| Ensembl ID | ENSMUSG00000027371 |
| Bio databases IDs | |
| Aliases | fumarylacetoacetate hydrolase domain containing 2A |
| Synonyms | 1500003K14Rik, B430104H02Rik, Cgi-105, Fahd2, fumarylacetoacetate hydrolase domain containing 2A, RGD1563674 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fahd2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit
- Protein of unknown function (DUF2848)
- enzyme
- HpaG-C-term
- oxaloacetate tautomerase
- Fumarylacetoacetate (FAA) hydrolase family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
- decreased circulating aspartate transaminase level
- decreased total body fat amount
- increased body length
- increased body weight
- increased hematocrit
- increased hemoglobin content
- increased mean corpuscular volume
- increased bone mineral density
- increased lean body mass
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm