Ggt7 Gene Summary [Mouse]

Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process and negative regulation of response to oxidative stress. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including glans of male genital tubercle; nervous system; and sensory organ. Orthologous to human GGT7 (gamma-glutamyltransferase 7). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ggt7
Official Name
gamma-glutamyltransferase 7 [Source:MGI Symbol;Acc:MGI:1913385]
Ensembl ID
ENSMUSG00000027603
Bio databases IDs NCBI: 207182 Ensembl: ENSMUSG00000027603
Aliases gamma-glutamyltransferase 7
Synonyms 1110017C11Rik, 6330563L03Rik, D20S101, gamma-glutamyltransferase 7, GGT4, GGTL3, GGTL5, γ-glutamyltransferase 7
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ggt7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Gamma-glutamyltranspeptidase
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • early missed abortion
  • metabolic syndrome X
  • coronary artery disease
  • neuroticism
  • rotator cuff injury
  • myocardial infarction
regulated by
regulates
role in cell
  • downregulation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ggt7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • glutathione biosynthetic process
  • glutathione catabolic process

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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