Ndst3 Gene Summary [Mouse]
Enables N-acetylglucosamine deacetylase activity and heparan sulfate N-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including exocrine system; future brain; genitourinary system; nervous system; and retina. Orthologous to human NDST3 (N-deacetylase and N-sulfotransferase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Ndst3 |
| Official Name | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 [Source:MGI Symbol;Acc:MGI:1932544] |
| Ensembl ID | ENSMUSG00000027977 |
| Bio databases IDs | |
| Aliases | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 |
| Synonyms | 4921531K01Rik, 4930511P15Rik, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3, N-deacetylase/N-sulphotransferase (heparan glucosaminyl) 3, N-HSST 3 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ndst3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- carboxylic ester hydrolase
- sulfotransferase
- [heparan sulfate]-glucosamine N-sulfotransferase
- N-acetylglucosamine deacetylase
- Sulfotransferase domain
- enzyme
- deacetylase
- Sulfotransferase family
- heparan sulfate-N-deacetylase
Pathways
Biological processes and signaling networks where the Ndst3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown