Cavin4 Gene Summary [Mouse]
Predicted to enable GTPase activator activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in Z disc; caveola; and sarcoplasm. Is expressed in cardiovascular system; lung; and skeletal muscle. Orthologous to human CAVIN4 (caveolae associated protein 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cavin4 |
| Official Name | caveolae associated 4 [Source:MGI Symbol;Acc:MGI:1915266] |
| Ensembl ID | ENSMUSG00000028348 |
| Bio databases IDs | |
| Aliases | caveolae associated 4 |
| Synonyms | 2310039E09Rik, caveolae associated 4, caveolae associated protein 4, MURC, RGD1310395 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cavin4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PTRF/SDPR family
- GTPase activator
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Plasma Membrane
- sarcoplasm
- caveolae
- Z line
- transverse tubules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cavin4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle organ development
- regulation of gene expression
- cell differentiation
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- Z disc
- caveola
- sarcoplasm
- cytoplasm
- sarcolemma
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding