CAVIN4 Gene Summary [Human]
This gene encodes a protein containing two coiled-coil regions. The encoded protein promotes Rho/ROCK (Rho-kinase) signaling in cardiac muscles cells, and may facilitate myofibrillar organization. [provided by RefSeq, Jun 2013]
Details
| Type | Protein Coding |
| Official Symbol | CAVIN4 |
| Official Name | caveolae associated protein 4 [Source:HGNC Symbol;Acc:HGNC:33742] |
| Ensembl ID | ENSG00000170681 |
| Bio databases IDs | |
| Aliases | caveolae associated protein 4, muscle-restricted coiled-coil protein |
| Synonyms | 2310039E09Rik, caveolae associated 4, caveolae associated protein 4, MURC, RGD1310395 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CAVIN4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PTRF/SDPR family
- GTPase activator
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Plasma Membrane
- sarcoplasm
- caveolae
- Z line
- transverse tubules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CAVIN4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- muscle organ development
- regulation of gene expression
- cell differentiation
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- Z disc
- caveola
- sarcoplasm
- cytoplasm
- sarcolemma
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding