Cavin4 Gene Summary [Rat]

Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in caveola. Orthologous to human CAVIN4 (caveolae associated protein 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cavin4
Official Name
caveolae associated protein 4 [Source:RGD Symbol;Acc:1310395]
Ensembl ID
ENSRNOG00000008027
Bio databases IDs NCBI: 313225 Ensembl: ENSRNOG00000008027
Aliases caveolae associated protein 4
Synonyms 2310039E09Rik, caveolae associated 4, caveolae associated protein 4, MURC, RGD1310395
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cavin4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PTRF/SDPR family
  • GTPase activator
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cardiac hypertrophy
regulated by
regulates
  • ERK1/2
  • DNA endogenous promoter
  • RNA polymerase II
  • DNA promoter
role in cell
  • activation in
  • accumulation in
  • distension
  • distension in
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Plasma Membrane
  • sarcoplasm
  • caveolae
  • Z line
  • transverse tubules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cavin4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • muscle organ development
  • regulation of gene expression
  • cell differentiation
  • positive regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • Z disc
  • caveola
  • sarcoplasm
  • cytoplasm
  • sarcolemma
  • cytosol
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.