Ppbp

Enables chemokine activity. Acts upstream of or within leukocyte migration involved in inflammatory response. Predicted to be located in platelet alpha granule. Predicted to be active in extracellular space. Is expressed in genitourinary system; gut; hemolymphoid system; and liver lobe. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to human PPBP (pro-platelet basic protein). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ppbp gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.