Ppbp

Predicted to enable chemokine activity. Involved in positive regulation of granulocyte chemotaxis. Predicted to be located in platelet alpha granule. Biomarker of acute myocardial infarction and hypospadias. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to human PPBP (pro-platelet basic protein). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ppbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ppbp gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.